Anopheles quadrimaculatus is a common summer mosquito that is typically active at night, preferring to rest in dark corners of buildings, stables, hollow trees, and other shelters during the day. The species overwinters in the adult stage and is typically found in habitats with permanent or semi-permanent water. Larvae develop in clear waters with low vegetation and/or floating debris such as those found in swamps, along the edges of ponds, and slow moving streams. The development period can last from 12 - 20 days, depending on the temperature, with pupal development occurring in 2 - 6 days. A. quadrimaculatus feeds on mammals and will readily enter homes seeking a blood meal. This species is the most important potential vector of malaria in the United States.
The Biology of Anopheles quadrimaculatus Say Claudia M. O'Malley, Burlington County Mosquito Extermination Commission